Those words were ringing in my ears when the first reports of the Mexican swine flu outbreak began trickling in few days ago. Dozens of young, otherwise healthy men were dying. Was this an encore of the infamous 1918 pandemic? Another SARS? Patients killed by their own overzealous immune systems (“cytokine storms”)? Or poor patients who came to the hospital too late to be saved? Then came lab reports of an unusually cosmopolitan swine/avian/human virus, with genetic links to two continents. This sort of thing doesn’t just happen. An awful lot of things have to happen first to make it possible.
“Disease is an outcome.” Wildlife biologist Milt Friend said that to me years ago when I was working on a story about the emergence of a frightening new virus just beginning to sweep across the country: West Nile. Friend had helped found the National Wildlife Health Center (a sort of CDC for critters), which was handling crow necropsies. After rattling off a disturbingly long list of wildlife die-offs from the last 30 years, he stopped, looked me in the eye and with a determined passion born of heartbreak said those four words. He had seen more than his share of ducks dropping dead — by the millions — from duck plague, and frogs with way too many legs, and “Mad Deer,” wobbling around with a version of the same ailment that causes Mad Cow. These were not random natural phenomena, but disasters aided and abetted by human action. Disease is an outcome.
Those words were ringing in my ears when the first reports of the Mexican swine flu outbreak began trickling in few days ago. Dozens of young, otherwise healthy men were dying. Was this an encore of the infamous 1918 pandemic? Another SARS? Patients killed by their own overzealous immune systems (“cytokine storms”)? Or poor patients who came to the hospital too late to be saved? Then came lab reports of an unusually cosmopolitan swine/avian/human virus, with genetic links to two continents. This sort of thing doesn’t just happen. An awful lot of things have to happen first to make it possible.
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Hi Tech / Low Tech: Lab in Cell Phone, Origami Diagnostics and Looking for the Unknown Germ12/23/2008 Bio photonics. Until yesterday, when a story on Wired magazine’s website about a “MacGyveresque” cell phone lit up Twitter universe, I hadn’t a clue. This particular cell phone, developed by Aydogan Ozcan’s lab at UCLA, doubles as a cytometer that can analyze blood cells for disease based on the cells’ light diffraction signatures. In short, rapid diagnostics literally at the speed of light in a portable package that fits in the palm of one’s hand. And as a cherry on the good news sundae, all the physical parts — an LED, a webcam, the phone itself — are off the shelf and cheap.
The implications for public health, particularly in poor developing countries, are, of course, enormous. This also has the potential to be a game-changer across the board, putting a “lab” in every doctor — or community health worker’s — pocket, dramatically reducing the time and cost of tests. Imagine: health-care costs that go down. (Although, as my colleague Ed Jezierski at InSTEDD points out, if it turns out that proprietary component of the test is expensive, the bargain disappears.) The Wired story was grouped on TrackerNews with a Technology Review article providing a more detailed explanation of the imaging system (which can also be used for testing water): I knew I’d seen that face before. Those cheeks. Those whiskers. That long, long tail. The giant African pouched rat, a.k.a. the giant Gambian pouched rat (Cricetomysgambianus), was all over the headlines five years ago, fingered as the likely culprit in a first-ever outbreak in the U.S. of monkeypox (a smallpox relative).
Shift continents and the villain becomes a hero. In fact, a “HeroRAT,” with a genius for sniffing out landmines and diagnosing TB. Welcome!
Like the TrackerNews aggregator, the Editor’s Blog focuses on health (human, animal, plant, and environmental), humanitarian work, and the technologies that support both. The website features links to news, research and resources, while the blog provides a little more depth and context. Every humanitarian crisis has a health component. Every serious outbreak of disease has a humanitarian dimension. This now plays out against a backdrop of climate change. Altered weather patterns trigger floods and droughts that can affect food supplies, drive regional conflicts and expand the range of vector-borne diseases. In an ever-flattening world, regional disasters can quickly go global, while global events can have devastating local consequences. It is all of a piece. |
backgroundThe TrackerNews Project was a demo aggregator I developed for InSTEDD, an independent spin-off of Google.org's humanitarian practice. It covered health issues, humanitarian work and technology. archives
November 2013
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